February 8, 2023
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Inverse Link Found for Antioxidant Levels, All-Cause Dementia – Consumer Health News


WEDNESDAY, May 4, 2022 (HealthDay News) – Antioxidants such as serum levels of lutein + zeaxanthin and β-cryptoxanthin are all linked to reduced risk of dementia, according to a study published online on May 4. Neurology.

May from the National Institute on Aging in Baltimore. Bedouin, Ph.D., MPH, and colleagues examined the association of antioxidant vitamins and carotenoids and the association of antioxidant vitamins and carotenoids in U.S. adults using data from National Health. Nutrition testing survey (1988 to 1994) linked to centers for Medicare and Medicaid-Medicare follow-up data. A total of 7,283 participants, aged 45 to 90, were followed at Baseline for 26 years.

Researchers found that serum lutein + xanthine was associated with a reduced risk for universal dementia (age 65 years or older) even in lifestyle-adjusted models (risk ratio, 0.93 per standard deviation), but this association was eroded. Comparison with a socio-economic status-compatible model (risk ratio, 0.92). For age- and gender-compatible models, there is a contrast between serum β-cryptoxanthin (increase per standard deviation) and all-cause dementia (risk ratio, 0.86 and 0.86 for 45 years and older and 65 years and older, respectively). Relationships seen. ; In the socio-economic status-adjusted models, the association was maintained (hazard ratio, 0.89 and 0.88 for 45 years and older and 65 years and older, respectively) but it was reduced in later models. Investigators have observed antagonistic interactions, indicating the protective effect of a carotenoid on low levels of other carotenoids or antioxidant vitamins.

“Expanding human cognitive functioning is an important public health challenge,” Bedouin said in a statement. “Antioxidants can help protect the brain from oxidative stress, which can lead to cell damage. Further research is needed to test whether adding these antioxidants can protect the brain from dementia.”

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